The NFL and the Los Angeles Rams released the team’s 2016 schedule on Thursday, April 14. The slate includes a home game in London against the New York Giants and a Monday Night Football opener against the rival San Francisco 49ers.
Here is the full schedule:
| Week | Date | Opponent | Time | Network |
| 1 | 9/12/16 | @ San Francisco 49ers | 7:20 p.m. PT | ESPN |
| 2 | 9/18/16 | Seattle Seahawks | 1:05 p.m. PT | FOX |
| 3 | 9/25/16 | @ Tampa Bay Buccaneers | 1:05 p.m. PT | FOX |
| 4 | 10/2/16 | @ Arizona Cardinals | 1:25 p.m. PT | FOX |
| 5 | 10/9/16 | Buffalo Bills | 1:25 p.m. PT | CBS |
| 6 | 10/16/16 | @Detroit Lions | 10:00 a.m. PT | FOX |
| 7 | 10/23/16 | New York Giants | 6:30 a.m. PT | NFL Net. |
| 8 | BYE | |||
| 9 | 11/6/16 | Carolina Panthers | 1:05 p.m. PT | FOX |
| 10 | 11/13/16 | @ New York Jets | 10:00 a.m. PT | FOX |
| 11 | 11/20/16 | Miami Dolphins | 1:05 p.m. PT | FOX |
| 12 | 11/27/16 | @ New Orleans Saints | 10:00 a.m. PT | FOX |
| 13 | 12/4/16 | @ New England Patriots | 10:00 a.m. PT | FOX |
| 14 | 12/11/16 | Atlanta Falcons | 1:25 p.m. PT | FOX |
| 15 | 12/18/16 | @ Seattle Seahawks | 5:25 p.m. PT | NBC/NFL |
| 16 | 12/24/16 | San Francisco 49ers | 1:25 p.m. PT | FOX |
| 17 | 1/1/17 | Arizona Cardinals | 1:25 p.m. PT | FOX |
